- Silvia Kal (2 movies)
- Silvia Curiel (1 movie)
- Silvia Colloca (1 movie)
- Silvano Marchetto (1 movie)
- Silvana Bosi (1 movie)
- Silas Carson (6 movies)
- Sigourney Weaver (16 movies)
- Signe Egholm Olsen (1 movie)
- Sigmund Bøe (1 movie)
- Sigitas Rackys (1 movie)
- Sigal Diamant (1 movie)
- Sig Frohlich (1 movie)
- Sierra McCormick (2 movies)
- Sienna Miller (9 movies)
- Sienna Guillory (8 movies)
- Siena LaGambina (1 movie)
- Sidney S. Liufau (1 movie)
- Sidney Poitier (1 movie)
- Sidney Mende-Gibson (1 movie)
- Sidney Johnston (1 movie)
- Sidney Beitz (1 movie)
- Sidné Anderson (1 movie)
- Sid Mitchell (1 movie)
- Sid Haig (2 movies)
- Sid Dawson (1 movie)
- Sid Caesar (1 movie)
- Sibyl Santiago (1 movie)
- Sibusisu Moyo (1 movie)
- Sian Thomas (2 movies)
- Sian Scott (1 movie)
- Siân Phillips (1 movie)
- Sian Grace Phillips (1 movie)
- Shyloh Oostwald (1 movie)
- Shyann McClure (1 movie)
- Shyaam Karra (1 movie)
- Shuna Lemoine (1 movie)
- Shun Sugata (4 movies)
- Shulie Cowen (1 movie)
- Shuler Hensley (2 movies)
- Shû Ôe (1 movie)
- Shû Nakajima (1 movie)
- Shu Lan Tuan (2 movies)
- Shu Chen (1 movie)
- Shruti Tewari (1 movie)
- Shruti Bapna (1 movie)
- Shree Crooks (1 movie)
- Shravanthi Sainath (1 movie)
- Shozo Iizuka (1 movie)
- Showtaro Morikubo (1 movie)
- Shoshana Bush (1 movie)