- Sayed Badreya (4 movies)
- Scott Caan (4 movies)
- Scott Porter (4 movies)
- Seamus Davey-Fitzpatrick (4 movies)
- Sean Biggerstaff (4 movies)
- Sean Bridgers (4 movies)
- Sean Pertwee (4 movies)
- Sebastian Hülk (4 movies)
- Seth Adkins (4 movies)
- Seth Green (4 movies)
- Sharon Stone (4 movies)
- Shawn Ashmore (4 movies)
- Shawn Hatosy (4 movies)
- Shefali Chowdhury (4 movies)
- Sherri Shepherd (4 movies)
- Shun Sugata (4 movies)
- Sissy Spacek (4 movies)
- Socratis Otto (4 movies)
- Sope Aluko (4 movies)
- Spencer Locke (4 movies)
- Spencer Wilding (4 movies)
- Spike Jonze (4 movies)
- Stephanie Szostak (4 movies)
- Stephen Bishop (4 movies)
- Stephen Colbert (4 movies)
- Stephen R. Hart (4 movies)
- Stephen Rea (4 movies)
- Sterling Jerins (4 movies)
- Steve Eastin (4 movies)
- Steve Witting (4 movies)
- Steven Mackintosh (4 movies)
- Sugar Lyn Beard (4 movies)
- Sullivan Stapleton (4 movies)
- S. Epatha Merkerson (3 movies)
- Sab Shimono (3 movies)
- Saffron Burrows (3 movies)
- Sala Baker (3 movies)
- Sam Douglas (3 movies)
- Sarah Baker (3 movies)
- Sarah Bolger (3 movies)
- Sarah Clarke (3 movies)
- Sarah Dumont (3 movies)
- Sarah Roemer (3 movies)
- Sarah Thompson (3 movies)
- Sasha Alexander (3 movies)
- Scarlett Byrne (3 movies)
- Scott A. Martin (3 movies)
- Scott Eastwood (3 movies)
- Scott G. Anderson (3 movies)
- Scott Menville (3 movies)