- Simon Chandler (3 movies)
- Simon Cormi (1 movie)
- Simon Cox (1 movie)
- Simon Day (1 movie)
- Simon Delaney (3 movies)
- Simon Fisher-Becker (1 movie)
- Simon Girard (1 movie)
- Simon Gleeson (1 movie)
- Simon Green (1 movie)
- Simon Grover (1 movie)
- Simon Harrison (1 movie)
- Simon Helberg (2 movies)
- Simon J. Williamson (1 movie)
- Simon Kassianides (2 movies)
- Simon Kunz (3 movies)
- Simon Lenagan (1 movie)
- Simon McBurney (9 movies)
- Simon Merrells (1 movie)
- Simon Nehan (1 movie)
- Simon Pegg (18 movies)
- Simon Pidgeon (1 movie)
- Simon Reithner (1 movie)
- Simon Rex (1 movie)
- Simon Reynolds (1 movie)
- Simon Russell Beale (2 movies)
- Simon Shorten (1 movie)
- Simon Stone (1 movie)
- Simon Wong (1 movie)
- Simon Woods (1 movie)
- Simona Caparrini (1 movie)
- Simona Williams (1 movie)
- Simone Kessell (2 movies)
- Simone Kirby (1 movie)
- Simone Spinazze (1 movie)
- Simonetta Stefanelli (1 movie)
- Sinbad (2 movies)
- Sincere L. Bobb (1 movie)
- Sinéad Cusack (2 movies)
- Sinead Matthews (2 movies)
- Sinead O'Keefe (1 movie)
- Sinead Watters (1 movie)
- Sinjin Venegas (1 movie)
- Sinqua Walls (1 movie)
- Siobhan Fallon (5 movies)
- Siobhan Flynn (1 movie)
- Siobhan Redmond (1 movie)
- Siobhan Reilly (1 movie)
- Siobhan Williams (1 movie)
- Sir Maejor (1 movie)
- Sissy Spacek (4 movies)