- Melissa Cobb (1 movie)
- Melissa De Sousa (1 movie)
- Melissa Disney (1 movie)
- Melissa Galloway (1 movie)
- Melissa George (3 movies)
- Melissa Goodwin Shepherd (1 movie)
- Melissa Hayden (1 movie)
- Melissa Jaffer (1 movie)
- Melissa Kurtz (1 movie)
- Melissa Lem (1 movie)
- Melissa Leo (14 movies)
- Melissa Lloyd-Wade (1 movie)
- Melissa Maria Gonzalez (1 movie)
- Melissa McBride (1 movie)
- Melissa McCarthy (9 movies)
- Melissa McMeekin (2 movies)
- Melissa Molinaro (1 movie)
- Melissa Ordway (3 movies)
- Melissa Paulo (2 movies)
- Melissa Rae Mahon (1 movie)
- Melissa Rauch (2 movies)
- Melissa Roxburgh (1 movie)
- Melissa Sagemiller (2 movies)
- Melissa Steinman (1 movie)
- Melissa Stribling (1 movie)
- Melissa Sturm (3 movies)
- Melissa Tang (1 movie)
- Melita Jurišić (1 movie)
- Mella Carron (1 movie)
- Mellan Mitchell (1 movie)
- Mellany Gandara (1 movie)
- Mélodie Simard (1 movie)
- Melody Weintraub (1 movie)
- Melody Zara (1 movie)
- Melonie Diaz (3 movies)
- Melora Hardin (2 movies)
- Melora Walters (1 movie)
- Melvin Brown (1 movie)
- Mena Suvari (3 movies)
- Menyone DeVeaux (1 movie)
- Merab Ninidze (1 movie)
- Mercedes Leggett (2 movies)
- Mercedes McCambridge (1 movie)
- Mercedes Ngoh (1 movie)
- Meredith Braun (1 movie)
- Meredith Droeger (1 movie)
- Meredith McGeachie (1 movie)
- Meredith Salenger (1 movie)
- Meredith Scott Lynn (1 movie)
- Meredith Travers (1 movie)