- Debra Messing (3 movies)
- Debra Monk (2 movies)
- Debra Paget (1 movie)
- Debra Winger (1 movie)
- Debra-Jayne Brown (1 movie)
- Debrah Neal (1 movie)
- Debralee Scott (1 movie)
- Debrianna Mansini (1 movie)
- Declan Hannigan (1 movie)
- Declan Mulvey (1 movie)
- Declan Swift (1 movie)
- Dee Bradley Baker (3 movies)
- Dee Dee Rescher (1 movie)
- Dee Donavan (1 movie)
- Dee Jay Jackson (2 movies)
- Dee Macaluso (1 movie)
- Dee Wallace (1 movie)
- Deema Aitken (1 movie)
- Deena Beasley (1 movie)
- Deep Roy (3 movies)
- Deepak Chopra (1 movie)
- Deepak Dobriyal (1 movie)
- Deidre Washington (1 movie)
- Deirdre Laird (1 movie)
- Deke Anderson (1 movie)
- Deke Richards (1 movie)
- Deke Sharon (2 movies)
- Delaney Hamilton (1 movie)
- Delilah Picart (1 movie)
- Delilah Sexton (1 movie)
- Delka Nenkova (1 movie)
- Della Saba (1 movie)
- Delphine Chanéac (1 movie)
- Delphine Chuillot (1 movie)
- Delroy Lindo (5 movies)
- Delta Burke (1 movie)
- Demetra Raven (1 movie)
- Demetri Goritsas (7 movies)
- Demetri Martin (3 movies)
- Demetrius Grosse (1 movie)
- Demetrius Joyette (1 movie)
- Demi Lovato (1 movie)
- Demi Moore (9 movies)
- Demián Bichir (4 movies)
- Demoine Kinney (1 movie)
- Demord Dann (1 movie)
- Dempsey Pappion (1 movie)
- Denai Gracie (1 movie)
- Denavaka Hamine (1 movie)
- Dendrie Taylor (3 movies)